44 Additionally, anergic cells Commonly retain a greater susceptibility to apoptosis Except if anti-apoptotic proteins such as BCL2 are overexpressed, as is the case for CLL cells.45 In fact, most major therapeutic improvements developing in the last decade are relevant to the inhibition of BCR and BCL2-mediated signaling. Di dunia https://juliek429irz7.daneblogger.com/profile