Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors within the central nervous procedure, conolidine modulates alternate molecular targets. A Science Advances review found that conolidine interacts With all the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://painkillerconolidine20630.howeweb.com/39206532/conolidin-to-replace-traditional-painkillers-fundamentals-explained