Conolidine’s analgesic effects stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors from the central nervous system, conolidine modulates alternate molecular targets. A Science Innovations analyze discovered that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabilit... https://whatischronicpain09754.dgbloggers.com/39336774/an-unbiased-view-of-alternative-natural-pain-relief-to-replace-traditional-painkillers